The Science Behind DNA Software:

John SantaLucia:  The company was formed in December 2000 and is the premier provider of nucleic acid hybridization and thermodynamic solutions.  Its OMP^TM software is based on the pioneering research of its Chief Scientific Officer, Dr. John SantaLucia, who is a Wayne State University professor, well-respected leader in his field, world-renowned consultant, and member of several national grant review committees.  Dr. SantaLucia's research has been cited by over 4000 publications.  Dr. SantaLucia directs all of the company’s scientific endeavors.

OMP Platform:  DNA Software combines science and software to enable industrial genomics through advances in technologies based on nucleic acids - the fundamental building blocks of the genome. The company's first software platform, OMP^TM (Oligonucleotide Modeling Platform^TM), models in silico the folding and hybridization of single-stranded nucleic acids with great accuracy. This enables the effective design of primers and probes for complex assays such as microarrays, microfluidics applications and multiplex PCR. The company combines OMP^TM with scientific consulting, custom software development, and custom laboratory research to deliver state-of-the-art support for designing and developing of nucleic acid based technologies.

Continuous R&D and Improvement:  DNA Software’s products and services are the best in its class.  Its software successfully incorporates all of the most advanced nearest-neighbor and multistate thermodynamics.  In addition to including all of the most current publically available thermodynamic parameters, DNA Software has large proprietary databases of supporting experimental data supported by several NIH SBIR grants.  Moreover, DNA Software is the only company that conducts ongoing wet lab R&D to experimentally validate and continuously add new assay parameters to its software.  Its algorithms are novel and proprietary.  The company’s team of scientists and software developers work very closely to create the best in silico solutions and most comprehensive products.