| The
core of DNA Software's product line is it's computational environment,
the Oligonucleotide Modeling Platform ("OMP"). OMP is a programmable
predictive modeling environment, which is used to develop customer-specific
applications. OMP takes all of the chemical and biological knowledge
and expertise developed by DNA Software scientists and Dr. SantaLucia's
previous work, and encapsulates it into a single, simulation
platform. Key technology features of OMP include:
- A
defined scripting language, allowing OMP to be "programmed"
for specific tasks necessary to users or client applications,
- Fully
encapsulated hybridization science functions which precisely
predict the DNA hybridization that will result from any specific
oligo experiment under a variety different design conditions,
including;
- Single-strand
optimal and sub-optimal unimolecular structure prediction,
recursive bimolecular hybridization algorithm,
- Customized
numerical analysis code for the solution of multiple coupled
hybridization equilibria,
- DNA
secondary structure display,
- Display
of species concentrations as a function of temperature,
- Interface
with the sequence and annotation data in the SNP database,
- Interface
with the Oracle, SQL and MS ACCESS database format,
- Rich
modeling functionality, including capabilities to predict
DNA microarray effectiveness, PCR and PCR multiplexed efficiency,
and oligo probe and primer interactions (dimerization),
- A
cutting edge peer-to-peer distributed computing architecture
which allows OMP to run across a cluster or network of PCs,
making OMP scalable and extremely fast,
- Cross-platform
capability to run on most any commercial Windows, Linux, or
Unix machine.
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