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  Innovative Solutions for Nucleic Acid Research


Publications


Year

Publication

2008

Saraiya, A.A., Lamichhane, T. N., Chow, C.S., SantaLucia, J., Jr., and Cunningham, P.R. (2008) "Identification and role of functionally important motifs in the 970 loop of Escherichia coli 16S ribosomal RNA", J. Mol. Biol., 376, 645-657.  Download PDF

2007

Bevilacqua, P.C., SantaLucia, J., Jr. (2007) "The Biophysics of RNA", ACS Chem. Biol., 2, 440–444.  Download PDF

2007

Aduri, R., Psciuk, B.T., Saro, P., Taniga, H., Schlegel, H.B., SantaLucia, J., Jr. (2007) "AMBER Force Field Parameters for the Naturally Occurring Modified Nucleosides in RNA", J. Chem. Theory and Comput., 3, 1464 -1475.  Download PDF

2007

SantaLucia, J., Jr. (2007) "Physical Principles and Visual-OMP Software for Optimal PCR Design", Methods in Molecular Biology: PCR Primer Design, Anton Yuryev, Ed., Humana Press, Totowa, New Jersey, Methods Mol. Biol.  

2006

Dhimitruka, I., SantaLucia, J., Jr. (2006) "Investigation of the Yamaguchi Esterification Mechanism. Synthesis of a Lux-S Enzyme Inhibitor Using an Improved Esterification Method", Organic Letters, 2006, 8, 47-50.  Download PDF
2005
Watkins, N.E., Jr., SantaLucia, J., Jr. (2005) "Nearest-neighbor thermodynamics of deoxyinosine pairs in DNA duplexes", Nucleic Acids Research, 2005, 33, 6258-6267.  Download PDF
2004
SantaLucia, J., Jr., Hicks, D. (2004) "The Thermodynamics of DNA Structural Motifs", Annu. Rev. Biophys. Biomol. Struct., 33, 415-40.  Download PDF
2004
Jang, S.B., Baeyens, K., Jeong, M.S., SantaLucia, J., Jr., Turner, D., Holbrook, S.R. (2004) "Structures of two RNA octamers containing tandem G-A base pairs", Acta Cryst., 60D, 829-835.  Download PDF
2004
Irani, R.J., SantaLucia, J., Jr. (2004) "Efficient preparation of 2-deoxy-3,5-di-O-p-toluoyl-a-D-ribofuranosyl chloride", SynLett, 2, 335-337.  Download PDF
2002
Irani, R.J., SantaLucia, J., Jr. (2002) "The Synthesis of Anti-fixed 3-Methyl-3-deaza-2'-deoxyadenosine and Other 3H-imidazo[4,5-c]pyridine Analogs", Nucleosides, Nucleotides & Nucleic Acids, 21, 737-751.  Download PDF
2002
Chow, C.S., Cunningham, P.R., Lee, K.S., Meroueh, M., SantaLucia, J., Jr., Varma, S. (2002) "Photoinduced cleavage by a rhodium complex at G-U mismatches and exposed guanines in large and small RNAs", Biochimie, 84, 859-868.  Download PDF
2002
Biswas, T., Clos, L.J., Santa Lucia, J., Jr., Mitra, S., Roy, R.J. (2002) "Binding of Specific DNA Base-pair Mismatches by N-Methylpurine-DNA Glycosylase and its implication in Initial Damage Recognition", Mol. Biol., 320, 503-513.  Download PDF
2001
Morosyuk, S.M., SantaLucia, J., Jr., Cunningham, P.R. (2001) "Structure and Function of the Conserved 690 Hairpin in Escherichia coli 16S ribosomal RNA: III. Instant Evolution Studies", Mol. Biol., 307, 213-221.  Download PDF
2001
Morosyuk, S.M., Cunningham, P.R., SantaLucia, J., Jr. (2001) "Structure and Function of the Conserved 690 Hairpin in Escherichia coli 16S ribosomal RNA: II. NMR Solution Structure", Mol. Biol., 307, 197-211.  Download PDF
2000
Morosyuk, S.V., Lee, K., SantaLucia, J., Jr., & Cunningham, P.R. J. (2000) "Structure and Function of the Conserved 690 Hairpin in Escherichia coli 16S ribosomal RNA: Analysis of the stem nucleotides", Mol. Biol., 300, 113-126.  Download PDF
2000
Meroueh, M., Grohar, P.J., Qiu, J., SantaLucia, J., Jr., Scaringe, S.A., Chow, C.S. (2000) "Unique Structural and Stabilizing Roles for the Individual Pseudouridine Residues in the 1920 Region of Escherichia coli 23S rRNA", Nucleic Acids Res., 28, 2075-2083.  Download PDF
2000
Bommarito, S., Peyret, N., SantaLucia, J., Jr. (2000) "Thermodynamic parameters for DNA sequences with dangling ends", Nucleic Acids Res., 28, 1929-1934.  Download PDF
1999
Irani, R., SantaLucia, J., Jr. (1999)  "The Synthesis of 5-iodocytidine Phosphoramidite for Heavy Atom Derivatization of RNA", Tetrahedron Lett., 40, 8961-8964.  Download PDF
1999
Blake, R.D., Bizzaro, J.W., Blake, J.D., Day, G.R., Delcourt, S.G., Knowles, J., Marx, K. A., SantaLucia, J., Jr. (1999) "Statistical Mechanical Simulation of Polymeric DNA Melting with MELTSIM", Bioinformatics, 15, 370-375.  Download PDF
1999
Peyret, N., Seneviratne, P.A., Allawi, H.T., SantaLucia, J., Jr. (1999) "Nearest-Neighbor Thermodynamics and NMR of DNA Sequences with Internal A-A, C-C, G-G, and T-T Mismatches", Biochemistry, 38, 3468-3477.  Download PDF
1998
Xia, T., SantaLucia, J., Jr., Burkard, M.E., Kierzek, R., Schroeder, S.J., Jiao, X., Cox, C., Turner, D.H. (1998) "Thermodynamic Parameters for an Expanded Nearest-Neighbor Model for Formation of RNA Duplexes with Watson-Crick Base Pairs", Biochemistry, 37, 14719-14735.  Download PDF
1998
Allawi, H.T., SantaLucia, J., Jr. (1998) "NMR Solution Structure of a DNA dodecamer containing single G-T Mismatches", Nucleic Acids Res., 26, 4925-4934.  Download PDF
1998
SantaLucia, J., Jr. (1998) "A Unified View of Polymer, Dumbbell, and Oligonucleotide DNA Nearest-Neighbor Thermodynamics", Proc. Natl. Acad. Sci. USA, 95, 1460-1465.  Download PDF
1998
Allawi, H.T., SantaLucia, J., Jr. (1998) "Nearest-Neighbor Thermodynamics of Internal A-C Mismatches in DNA: Sequence Dependence and pH Effects", Biochemistry, 37, 9435-9444.  Download PDF
1998
Allawi, H.T., SantaLucia, J., Jr. (1998) "Thermodynamics of Internal C-T Mismatches in DNA", Nucleic Acids Res., 26, 2694-2701.  Download PDF
1998
Allawi, H.T., SantaLucia, J., Jr. (1998) "Nearest Neighbor Thermodynamic Parameters for Internal G-A Mismatches in DNA", Biochemistry, 37, 2170-2179.  Download PDF
1998
Arghavani, M.B., SantaLucia, J., Jr., Romano, L.J. (1998) "Effect of Mismatched Complementary Strands and 5'-Change in Sequence Context on the Thermodynamics and Structure of Benzo[a]pyrene-Modified Oligonucleotides", Biochemistry, 37, 8575-8583.  Download PDF
1997
Leontis, N.B., SantaLucia, J., Jr. (Eds.) (1997) "Molecular Modeling of Nucleic Acids", ACS Symposium Series, 682, ACS pub., Washington, DC.
1997
Wu, M., SantaLucia, J., Jr., Turner, D.H. (1997) "Solution Structure of (rGGCAGGCC)2 by Two-Dimensional NMR and the Iterative Relaxation Matrix Approach", Biochemistry, 36, 4449-4460.  Download PDF
1997
Carter, R.J., Baeyens, K.J., SantaLucia, J., Jr., Turner, D.H., Holbrook, S.R. (1997) "The Crystal Structure of an RNA Oligomer Incorporating Tandem Adenosine-Inosine Mismatches", Nucleic Acids Res., 25, 4117-4122.  Download PDF
1997
SantaLucia, J., Jr., Turner, D.H. (1997) "Measuring the Thermodynamics of RNA Secondary Structure Formation", Biopolymers, 44, 309-319.  Download PDF
1997
Lee, K., Varma, S., SantaLucia, J., Jr., Cunningham, P.R. (1997) "In Vivo Determination of RNA Structure-Function Relationships: Analysis of the 790 Loop in Ribosomal RNA", J. Mol. Biol., 269, 732-743.  Download PDF
1997
Allawi, H.T., SantaLucia, J., Jr. (1997) "Thermodynamics and NMR of Internal G-T Mismatches in DNA", Biochemistry, 36, 10581-10594.  Download PDF
1996
SantaLucia, J., Jr., Allawi, H.T., Seneviratne, P.A. (1996) "Improved Nearest-Neighbor Parameters for Predicting DNA Duplex Stability", Biochemistry, 35, 3555-3562.  Download PDF
1995
SantaLucia, J., Jr., Shen, L., Cai, Z., Lewis, H., Tinoco, I., Jr. (1995) "Synthesis and NMR of RNA with Isotopic Enrichment in the Bases", Nucleic Acids Res., 23, 4913-4921.  Download PDF
1993
SantaLucia, J., Jr., Turner, D.H. (1993) "Structure of (rGGCGAGCC)2 in Solution from NMR and Restrained Molecular Dynamics", Biochemistry, 32, 12612-12623.  Download PDF
1993
Jaeger, J.A., SantaLucia, J., Jr., Tinoco, I., Jr. (1993) "Determination of RNA Structure and Thermodynamics", Ann. Rev. Biochem., 62, 255-287.  Download PDF
1992
SantaLucia, J., Jr., Kierzek, R., Turner, D.H. (1992) "Context Dependence of Hydrogen Bond Free Energy Revealed by Substitutions in an RNA Hairpin", Science, 256, 217-219.  Download PDF
1991
He, L., Kierzek, R., SantaLucia, J., Jr., Walter, A.E., Turner, D.H. (1991) "Nearest-Neighbor Parameters for GU Mismatches: GU/UG Is Destabilizing in the Contexts CGUG, UGUA, and AGUU but Stabilizing in GGUC", Biochemistry, 30, 11124-11132.  Download PDF
1991
SantaLucia, J., Jr., Kierzek, R., Turner, D.H. (1991) "Stabilities of Consecutive AC, CC, GG, UC, and UU Mismatches  in RNA Internal Loops: Evidence for Stable Hydrogen-Bonded UU and CC+ Pairs", Biochemistry, 30, 8242-8251.
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1991
SantaLucia, J., Jr., Kierzek, R., Turner, D.H. (1991) "Functional Group Substitutions as Probes of Hydrogen Bonding between GA Mismatches in RNA Internal Loops", J. Am. Chem. Soc., 113, 4313-4322.  Download PDF
1990
SantaLucia, J., Jr., Kierzek, R., Turner, D.H. (1990) "Effects of GA Mismatches on the Structure and Thermodynamics of RNA Internal Loops", Biochemistry, 29, 8813-8819.  Download PDF


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